Rythmic™ Evolution

  • Ambulatory Infusion Pump Rythmic Evolution Mini
  • Ambulatory Infusion Pump Rythmic Evolution Mini
  • Ambulatory Infusion Pump Rythmic Evolution options available for different drug volumes
  • Infusion Pump Rythmic Evolution System
    Rythmic Evolution system side
  • Rythmic Evolution Ambulatory Infusion Pump
    Micrel 16_ENG copy_ Website
  • Rythmic Evolution - Colour Coded Yellow for PCEA or other applications
    Micrel 14_ENG copy_ Website
  • Rythmic Evolution Mini - Colour Coded Yellow for PCEA or other applications
    Micrel 17_CutOut_ENG copy_ Website
  • Rythmic Evolution 500 Series - Colour Coded Yellow for PCEA or other applications
    Micrel 08_Website
  • Rythmic Evolution Case
  • Infusion Pump Rythmic Evolution 500 Series
    Rythmic Evolution Blue Lockbox
  • Micrel 11_ENG copy_ Website
  • Micrel 23_ENG copy_ Website

Rythmic™ Evolution is an ambulatory pump for Acute and Chronic Pain management, as well as other continuous infusion therapies such as Chemotherapy, Cystic Fibrosis, Primary Pulmonary HypertensionIVIG.

Key features of the Rythmic™ Evolution portable pump:

  • The new Rythmic™ Evolution brings Pain Management to a new era by interacting with the patient and allowing the patient to record his pain level during the therapy through an integrated Visual Analogue Scale (VAS)
  • A protocol library is included in the pump. Caregivers can titrate the selected infusion protocol, staying within pre-programmed safety limits
  • Custom menu with or without Bolus / Dose Limit / Loading dose to fit therapy protocols and avoid set up errors
  • Easy review of patient history thanks to easy-to-read history menu on the pump and display of graphs
  • Simplified set up menu with a 3-step start procedure: Enter Rate, Volume to Infuse and Start infusion.
  • Allows for "Preventive Maintenance" notices
  • Ability to print history and events on a portable printer or download on a PC
  • Connectivity to our proprietary mobile GPRS device IP-Connect™ Pack that allows for the best infusion monitoring service available today through our web based MicrelCare Service system

Rythmic™ Evolution is reducing unnecessary alarm activity

The pump has been designed to reduce most of uneccessary potential alarms whilst preserving full safety:

  • No air alarm thanks to the air-in-line eliminator incorporated in all sets
  • Automatic restart after occlusion release
  • Long battery autonomy (9 days at 2 ml/h) to decrease the frequency of battery alarms and related changes 

Rythmic™ Evolution offers "All in One" innovative, high safety, infusion sets

  • All sets include all pre-assembled components thus avoiding additional unsafe connections
  • Available in 100 ml or 200 ml version for integration into the pump or with Spike for external bags
  • Soft drug bag that is convenient to fill and prime manually or via the pump
  • Built-in anti free flow / back check valve, air eliminator, and extension line on all sets
Please visit our Infusion Sets section for more information.
Rythmic™ Evolution offers real mobility to patients
  • Small, ergonomic and compact for true and comfortable ambulatory therapies
  • Drug bags for volumes up to 200 ml placed in dedicated space inside the pump
  • Lightweight: 335 g with dry cell battery
  • Outstanding battery autonomy
The pump is also supported by a wide range of Accessories.

Please click on the Specifications Tab on the right to see the specifications of the Rythmic™ Evolution pump.

Delivery modes

Continuous,  Bolus only, Continuous + Bolus, Programmed Automatic Bolus (PAB)


+/- 5 %

Flow rate

0.1 to 100 ml/h

Programming units



0.1 to 99.9 mg/ml/0.1 to 999.9 µg/ml

Volume to infuse

1 to 9999 ml

Bolus dose

0 or from 0.1 to 60ml with 0.1ml increment

Bolus flow rate

100 ml/h, adjustable from 50 to 100 ml/h with 10 ml/h increment

Lockout interval

0 to 999 minutes

Special functions

Protocol libraries (60 protocol per library)

Lockable pump keyboard

Autopriming through the pump

Dose limit / x hours and  Bolus limit / x hours

Loading dose

Clinician bolus override

Mandatory priming (enabled, warning only, disabled)

Therapy monitoring

Recording of patient pain scores with visual analogue scale (VAS)

VAS available in the pump history, printable and computer downloadable

"Ready to Connect" to the MicrelCare System for therapy monitoring through the web.


0.1 to 2.0 ml/h

Automatic restart of infusion after occlusion release


Safety features

Air in line eliminating filter

Lockable protective cover for drug container

Code protected stop of infusion

Free flow protection 

Programming within protocol limits

Dedicated therapy front face for regional analgesia (PCEA/PCRA yellow color code)

Occlusion alarm levels

Low (0.8 +/- 0.4 = 0.4 - 1.2 bar)

Middle (1.2 +/-0.4 = 0.8 - 1.6 bar)

High (1.6 +/- 0.4 = 1.2 - 2.0 bar)

Alarms & warnings

Occlusion near end and end of infusion

Keyboard continuously pressed

Low and depleted battery

Dose limit, bolus limit

Open mechanism, preventive maintenance warnig

Access code levels



Protocol libraries programmed with "Rythmic™   Evolution Therapy Manager" computer software

Direct programming on the pump possible with code

History, infusion graph / printout and PC download

Yes, including 6500 time stamped events event log

Infusion graph, bolus graph/list, pain level/graph/list

 "Plug and play" print facility

Battery life

9 days at 2 ml/h

Power supply

100 to 240 V, 50-60 Hz (with optional adaptor KS5.01.615.4)

Weight with battery

300g for Mini Rythmic™ Evolution

335g for Rythmic™ Evolution

740g for Rythmic™ Organizer 500 series


130mm x 75mm x 46mm for Mini Rythmic™ Evolution (including 100 ml bag) 

130mm x 133mm x 46mm for Rythmic™ Evolution (including 200 ml bag)

157mm x 299mm x 82mm for Rythmic™ Organiser 500 series (including 500 ml standard bag)


Freedom without clinical compromise